SULT1E1 Antikörper

Produktnummer ABIN7882386

Dieser Maus Monoklonal Antikörper detektiert spezifisch SULT1E1 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SULT1E1 Antikörper (ABIN7882386)

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SULT1E1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CPTC-SULT1E1-1

Produktdetails anti-SULT1E1 Antikörper

Verwendungszweck: SULT1E1 Antibody / Estrogen Sulfotransferase

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for the SULT1E1 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SULT1E1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the SULT1E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Andere Bezeichnung: SULT1E1

Hintergrund: The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis