Rekombinanter Sortilin 1 Antikörper

Produktnummer ABIN7882337

Der Kaninchen Monoklonal anti-Sortilin 1 Antikörper (Klon 17S35) (ABIN7882337) detektiert spezifisch Sortilin 1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter Sortilin 1 Antikörper (ABIN7882337)

Target: Sortilin 1 (SORT1)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Sortilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 17S35

Produktdetails anti-Sortilin 1 Antikörper

Verwendungszweck: SORT1 Antibody / Sortilin

Aufreinigung: Affinity chromatography

Immunogen: A peptide sequence specific to Sortilin was used as the immunogen for the SORT1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SORT1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SORT1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Sortilin 1

Target: Sortilin 1 (SORT1)

Andere Bezeichnung: SORT1

Hintergrund: Sortilin (SORT1) is a type I transmembrane receptor belonging to the vacuolar protein sorting 10 (VPS10) domain receptor family. It is involved in intracellular protein trafficking, endocytosis, and sorting of a variety of ligands, including neurotrophins, lipoproteins, and enzymes. SORT1 plays an important role in neuronal viability, lipid metabolism, and protein transport between the Golgi apparatus and endosomes.

Altered expression or function of SORT1 has been associated with neurodegenerative disorders, cardiovascular disease, and lipid metabolism abnormalities. Research has linked SORT1 to regulation of low-density lipoprotein (LDL) cholesterol levels and to processes that influence neuronal growth and survival. Understanding SORT1’s biological roles can provide insights into both neurological function and metabolic health.

Using a high-quality SORT1 antibody enables reliable detection in applications such as western blot, immunohistochemistry, and immunofluorescence. A SORT1 antibody from NSJ Bioreagents ensures reproducibility and sensitivity for studies involving neuronal biology, lipid metabolism, and receptor-mediated signaling. Selecting the right SORT1 antibody is essential for generating accurate and consistent experimental results.

UniProt: Q99523

Pathways: Neurotrophin Signalübertragung