SKIP Antikörper

Produktnummer ABIN7882277

Der Maus Monoklonal anti-SKIP Antikörper (Klon PCRP-SNW1-2A1) (ABIN7882277) detektiert spezifisch SKIP in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SKIP Antikörper (ABIN7882277)

Target: SKIP

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-SNW1-2A1

Produktdetails

Verwendungszweck: SKIP Antibody / SNW1 / NCoA-62 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment of human protein was used as the immunogen for the SKIP antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SKIP antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SKIP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: SKIP

Hintergrund: Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

UniProt: Q13573