Septin 5 Antikörper

Produktnummer ABIN7882234

Der Kaninchen Polyklonal anti-Septin 5 Antikörper wird verwendet zum Nachweis von Septin 5 in Proben von Human und Ratte. Er wurde validiert für WB und FACS.

Kurzübersicht für Septin 5 Antikörper (ABIN7882234)

Target: Septin 5 (SEPT5)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-Septin 5 Antikörper

Verwendungszweck: SEPT5 Antibody / Septin 5

Sequenz: HYENYRAHCI QQMTSKLTQD

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids HYENYRAHCIQQMTSKLTQD were used as the immunogen for the SEPT5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SEPT5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SEPT5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Septin 5

Target: Septin 5 (SEPT5)

Andere Bezeichnung: SEPT5

Hintergrund: This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis