SELPLG Antikörper
Kurzübersicht für SELPLG Antikörper (ABIN7882228)
Target
Alle SELPLG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD162 Antibody / PSGL-1 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant human PSGL-1 /CD162 protein was used as the immunogen for the CD162 antibody.
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Isotyp
- IgM, kappa
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Applikationshinweise
- Optimal dilution of the CD162 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CD162 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SELPLG (Selectin P Ligand (SELPLG))
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Andere Bezeichnung
- CD162
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Hintergrund
- CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
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UniProt
- Q14242
Target
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