Retinoid X Receptor gamma Antikörper

Produktnummer ABIN7882160

Der Maus Monoklonal anti-Retinoid X Receptor gamma Antikörper (Klon PCRP-RXRG-5C9) (ABIN7882160) detektiert spezifisch Retinoid X Receptor gamma in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Retinoid X Receptor gamma Antikörper (ABIN7882160)

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoid X Receptor gamma Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-RXRG-5C9

Produktdetails anti-Retinoid X Receptor gamma Antikörper

Verwendungszweck: RXR gamma Antibody / RXRG (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant human RXR gamma protein was used as the immunogen for the RXRG antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RXR gamma antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RXR gamma antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Retinoid X Receptor gamma

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Andere Bezeichnung: RXR gamma

Hintergrund: Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RARa, RARb and RARg, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXRa, RXRb and RXRg, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.

UniProt: P78347

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway