Rekombinanter PROX1 Antikörper

Produktnummer ABIN7882055

Der Kaninchen Monoklonal anti-PROX1 Antikörper (Klon AOGA-16) (ABIN7882055) detektiert spezifisch PROX1 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter PROX1 Antikörper (ABIN7882055)

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PROX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: AOGA-16

Produktdetails anti-PROX1 Antikörper

Verwendungszweck: Prospero homeobox protein 1 Antibody / PROX1

Aufreinigung: Affinity chromatography

Immunogen: A peptide sequence specific to PROX1 protein was used as the immunogen for the Prospero homeobox protein 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Prospero homeobox protein 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The Prospero homeobox protein 1 antibody can be stored at -20oC.

Details zu PROX1

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Andere Bezeichnung: Prospero homeobox protein 1

Hintergrund: PROX1 is a homeobox transcription factor that orchestrates cell fate programs by binding target DNA motifs and recruiting co-regulators to modulate chromatin accessibility. It is widely studied for its roles in developmental patterning and maintenance of specialized cell identities, particularly within endothelial and neural lineages.

In vascular biology, PROX1 is a master regulator of lymphatic endothelial specification and maintenance, aligning gene expression with signaling inputs that guide vessel identity, remodeling, and tissue fluid balance. Beyond endothelium, PROX1 contributes to organ development and context-dependent transcriptional networks that shape differentiation, metabolism, and tissue architecture.

The Prospero homeobox protein 1 antibody enables specific detection of endogenous PROX1 in applications such as immunohistochemistry, immunofluorescence, western blot, and immunoprecipitation. Researchers use the Prospero homeobox protein 1 antibody from NSJ Bioreagents to quantify protein abundance, assess nuclear localization, and evaluate pathway engagement across primary tissues and model systems. With high specificity and consistent performance, the Prospero homeobox protein 1 antibody supports rigorous studies of transcriptional regulation, vascular biology, and cell differentiation.

UniProt: Q92786

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation