Rekombinanter P4HTM Antikörper
Kurzübersicht für Rekombinanter P4HTM Antikörper (ABIN7882047)
Target
Alle P4HTM Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- P4HTM Antibody / HIF Prolyl Hydroxylases / HIFPH4
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Aufreinigung
- Affinity chromatography
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Immunogen
- A synthetic peptide derived from human HIF Prolyl Hydroxylases was used as the immunogen for the P4HTM antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the P4HTM antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the P4HTM antibody at -20oC.
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- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
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Andere Bezeichnung
- P4HTM
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Hintergrund
- Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. [UniProt]
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UniProt
- Q9NXG6
Target
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