Rekombinanter POLG Antikörper

Produktnummer ABIN7881999

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch POLG in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter POLG Antikörper (ABIN7881999)

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser POLG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 24P93

Produktdetails anti-POLG Antikörper

Verwendungszweck: POLG Antibody / DNA polymerase subunit gamma 1

Aufreinigung: Affinity chromatography

Immunogen: A peptide sequence specific to DNA polymerase subunit gamma 1 was used as the immunogen for the POLG antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the POLG antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the POLG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu POLG

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Andere Bezeichnung: POLG

Hintergrund: DNA polymerase subunit gamma 1 (POLG) is the catalytic subunit of the mitochondrial DNA polymerase complex, responsible for replication and repair of mitochondrial DNA. POLG ensures accurate DNA synthesis within mitochondria, which is essential for proper oxidative phosphorylation and cellular energy production.

Mutations in POLG are associated with a range of mitochondrial disorders, including progressive external ophthalmoplegia, Alpers-Huttenlocher syndrome, and ataxia-neuropathy syndromes. Studying POLG function helps researchers understand mitochondrial genome maintenance and the molecular basis of mitochondrial diseases.

Using a high-quality POLG antibody allows for sensitive detection of the protein in assays such as western blot, immunohistochemistry, and immunofluorescence. A POLG antibody from NSJ Bioreagents offers consistent performance, supporting studies in mitochondrial biology, genetic disorders, and DNA repair mechanisms. Choosing the right POLG antibody is critical for producing reliable and reproducible research results.

UniProt: P54098