PHPT1 Antikörper

Produktnummer ABIN7881938

Der Maus Monoklonal anti-PHPT1 Antikörper (Klon PHPT1-12053) (ABIN7881938) detektiert spezifisch PHPT1 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PHPT1 Antikörper (ABIN7881938)

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PHPT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PHPT1-12053

Produktdetails anti-PHPT1 Antikörper

Verwendungszweck: PHPT1 Antibody / Phosphohistidine phosphatase 1

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant human 14 kDa phosphohistidine phosphatase protein was used as the immunogen for the PHPT1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PHPT1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the PHPT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PHPT1

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Andere Bezeichnung: PHPT1

Hintergrund: PHPT1 (phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTAinsensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.

UniProt: Q9NRX4

Pathways: Positive Regulation of Peptide Hormone Secretion