PHPT1 Antikörper

Produktnummer ABIN7881935

Der Maus Monoklonal anti-PHPT1 Antikörper (Klon PHPT1-12054) (ABIN7881935) detektiert spezifisch PHPT1 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PHPT1 Antikörper (ABIN7881935)

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PHPT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: PHPT1-12054

Produktdetails anti-PHPT1 Antikörper

Verwendungszweck: Phosphohistidine phosphatase 1 Antibody / PHPT1 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant human 14 kDa phosphohistidine phosphatase protein was used as the immunogen for the Phosphohistidine phosphatase 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Phosphohistidine phosphatase 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Phosphohistidine phosphatase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PHPT1

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Andere Bezeichnung: Phosphohistidine phosphatase 1

Hintergrund: PHPT1 (phosphohistidine phosphatase 1), also known as 14 kDa phosphohistidine phosphatase, is a 125 amino acid enzyme belonging to the Janus protein family. Existing as a monomer in the cytoplasm, PHPT1 is an EDTAinsensitive phosphohistidine phosphatase. First identified in human adrenal gland, PHPT1 is highly expressed in skeletal muscle and heart, with lower expression in liver, pancreas and kidney. Overexpression of PHPT1 leads to specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides. PHPT1 is highly conserved among species, suggesting that it serves an essential functional role.

UniProt: Q9NRX4

Pathways: Positive Regulation of Peptide Hormone Secretion