NECAB1 Antikörper

Produktnummer ABIN7881751

Der Maus Monoklonal anti-NECAB1 Antikörper wird verwendet zum Nachweis von NECAB1 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für NECAB1 Antikörper (ABIN7881751)

Target: NECAB1 (N-terminal EF-Hand Calcium Binding Protein 1 (NECAB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NECAB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: NECAB1-7680

Produktdetails anti-NECAB1 Antikörper

Verwendungszweck: NECAB1 Antibody / N-terminal EF-hand calcium binding protein 1 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant human NECAB1 protein was used as the immunogen for the NECAB1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NECAB1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the NECAB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu NECAB1

Target: NECAB1 (N-terminal EF-Hand Calcium Binding Protein 1 (NECAB1))

Andere Bezeichnung: NECAB1

Hintergrund: Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP1 (N-terminal EF-hand calcium binding protein 1), also known as STIP-1 or neuronal calcium-binding protein 1 (NECAB1), is a 351 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and 2 EF-hand domains. Expressed in brain, EF-CBP1 interacts with copine 6 and Syntaxin, and exists as two alternatively spliced isoforms. The gene encoding EF-CBP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

UniProt: Q8N987