MSTN Antikörper

Produktnummer ABIN7881742

Der Kaninchen Polyklonal anti-MSTN Antikörper wird verwendet zum Nachweis von MSTN in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für MSTN Antikörper (ABIN7881742)

Target: MSTN (Myostatin (MSTN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSTN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MSTN Antikörper

Verwendungszweck: GDF8 Antibody / Myostatin

Sequenz: SGECEFVFLQ KYPH

Aufreinigung: Affinity purified

Immunogen: Amino acids SGECEFVFLQKYPH from the human protein were used as the immunogen for the GDF8 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GDF8 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the GDF8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MSTN

Target: MSTN (Myostatin (MSTN))

Andere Bezeichnung: GDF8

Hintergrund: Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals.

UniProt: O14793