Myogenin Antikörper
Kurzübersicht für Myogenin Antikörper (ABIN7881724)
Target
Alle Myogenin (MYOG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Myf-4 Antibody / MYOG / Myogenin
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Human recombinant protein was used as the immunogen for the Myf-4 antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the Myf-4 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot the Myf-4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
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Andere Bezeichnung
- Myf-4
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Hintergrund
- Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif.MyoD family members share about 80 % amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms tumor.
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UniProt
- P15173
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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