MFN2 Antikörper

Produktnummer ABIN7881650

Der Kaninchen Monoklonal anti-MFN2 Antikörper (Klon AOCA-13) (ABIN7881650) detektiert spezifisch MFN2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für MFN2 Antikörper (ABIN7881650)

Target: MFN2 (Mitofusin 2 (MFN2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MFN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: AOCA-13

Produktdetails anti-MFN2 Antikörper

Verwendungszweck: Mitofusin 2 Antibody / MFN2

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human Mitofusin 2 / MFN2 was used as the immunogen for the Mitofusin 2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Mitofusin 2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the Mitofusin 2 antibody at -20oC.

Details zu MFN2

Target: MFN2 (Mitofusin 2 (MFN2))

Andere Bezeichnung: Mitofusin 2

Hintergrund: Mitofusin 2 is a mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains (Probable). Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PRKN recruitment to dysfunctional mitochondria. [UniProt]

UniProt: O95140

Pathways: Skeletal Muscle Fiber Development