Der Kaninchen Monoklonal anti-MRPL11 Antikörper wird verwendet zum Nachweis von MRPL11 in Proben von Human. Er wurde validiert für WB, IHC, IF und ICC.
MRPL11
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
RB38899
unconjugated
Applikationshinweise
Optimal dilution of the MRPL11 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store the MRPL11 antibody at -20oC.
Target
MRPL11
(Mitochondrial Ribosomal Protein L11 (MRPL11))
Andere Bezeichnung
MRPL11
Hintergrund
MRPL11 antibody recognizes mitochondrial ribosomal protein L11, a component of the 39S large ribosomal subunit. MRPL11 contributes to mitochondrial protein synthesis by aiding translation of mRNAs encoded within mitochondrial DNA. Proper function of MRPL11 is essential for oxidative phosphorylation and maintenance of cellular energy metabolism.
Research with MRPL11 antibody has shown that altered expression of mitochondrial ribosomal proteins can impair respiratory chain activity, leading to mitochondrial dysfunction. Such disturbances are implicated in neuromuscular disorders, metabolic syndromes, and age-related decline in mitochondrial efficiency. MRPL11 expression is therefore of interest for studies of energy balance and disease pathogenesis.
Antibodies against MRPL11 are validated for use in western blot, immunohistochemistry, and immunofluorescence. These reagents help researchers analyze mitochondrial translation and investigate how ribosomal proteins contribute to cellular stress adaptation.
NSJ Bioreagents offers this MRPL11 antibody to support studies of mitochondrial protein synthesis and energy metabolism.