MBD3 Antikörper

Produktnummer ABIN7881628

Der Kaninchen Monoklonal anti-MBD3 Antikörper wird verwendet zum Nachweis von MBD3 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für MBD3 Antikörper (ABIN7881628)

Target: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser MBD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: AFEE-13

Produktdetails anti-MBD3 Antikörper

Verwendungszweck: MBD3 Antibody

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human MBD3 was used as the immunogen for the MBD3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MBD3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the MBD3 antibody at -20oC.

Details zu MBD3

Target: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Andere Bezeichnung: MBD3

Hintergrund: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The MBD3 gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. [RefSeq]

UniProt: O95983

Pathways: Chromatin Binding