L1CAM Antikörper

Produktnummer ABIN7881449

Der Maus Monoklonal anti-L1CAM Antikörper (Klon SPM275) (ABIN7881449) detektiert spezifisch L1CAM in ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für L1CAM Antikörper (ABIN7881449)

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser L1CAM Antikörper ist unkonjugiert

Applikation: ELISA

Güteklasse: Carrier-free

Klon: SPM275

Produktdetails anti-L1CAM Antikörper

Verwendungszweck: L1CAM Antibody / NCAM-L1 / CD171 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Homogenous suspension of 16-week human fetal brain cells were used as the immunogen for the L1CAM antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the L1CAM antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the L1CAM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu L1CAM

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Andere Bezeichnung: L1CAM

Hintergrund: Recognizes a cell surface protein of 220-240 kDa, identified as L1 cell adhesion molecule. The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, and adducted thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, and neural migration as well as in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm. This MAb is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin e.g. neuroblastoma and Schwannomas. It does not bind to pediatric or adult brain.

UniProt: P32004

Pathways: Synaptic Membrane