Rekombinanter CDH6 Antikörper

Produktnummer ABIN7881339

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CDH6 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CDH6 Antikörper (ABIN7881339)

Target: CDH6 (K-Cadherin (CDH6))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CDH6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: CDH6-9300R

Produktdetails anti-CDH6 Antikörper

Verwendungszweck: Recombinant K-Cadherin Antibody / Cadherin 6 / CDH6 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant human Cadherin 6 protein (CDH6) was used as the immunogen for the recombinant K-Cadherin antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant K-Cadherin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant K-Cadherin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CDH6

Target: CDH6 (K-Cadherin (CDH6))

Andere Bezeichnung: K-Cadherin

Hintergrund: This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

UniProt: P55285

Pathways: Cell-Cell Junction Organization