IGF2BP3 Antikörper
Kurzübersicht für IGF2BP3 Antikörper (ABIN7881187)
Target
Alle IGF2BP3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- IGF2BP3 Antibody
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Aufreinigung
- Affinity purified
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Immunogen
- A synthetic peptide specific to human Insulin-like growth factor 2 mRNA-binding protein 3 was used as the immunogen for the IGF2BP3 antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the IGF2BP3 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the IGF2BP3 antibody at -20oC.
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- IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))
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Andere Bezeichnung
- IGF2BP3
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Hintergrund
- RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. [UniProt]
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UniProt
- O00425
Target
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