HBA1 Antikörper

Produktnummer ABIN7881006

Der Kaninchen Polyklonal anti-HBA1 Antikörper wird verwendet zum Nachweis von HBA1 in Proben von Human und Maus. Er wurde validiert für WB und IHC (p).

Kurzübersicht für HBA1 Antikörper (ABIN7881006)

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HBA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HBA1 Antikörper

Verwendungszweck: Hemoglobin alpha Antibody / HBA1/2

Sequenz: AVHASLDKFL ASVSTVLTSK YR

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids AVHASLDKFLASVSTVLTSKYR from the human protein were used as the immunogen for the Hemoglobin alpha antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Hemoglobin alpha antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Hemoglobin alpha antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu HBA1

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Andere Bezeichnung: Hemoglobin alpha

Hintergrund: The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported.

UniProt: P69905