GTF2I Antikörper

Produktnummer ABIN7880866

Der Maus Monoklonal anti-GTF2I Antikörper (Klon PCRP-GTF2I-1A7) (ABIN7880866) detektiert spezifisch GTF2I in FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GTF2I Antikörper (ABIN7880866)

Target: GTF2I (General Transcription Factor III (GTF2I))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GTF2I Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: PCRP-GTF2I-1A7

Produktdetails anti-GTF2I Antikörper

Verwendungszweck: GTF2I Antibody / General transcription factor II-I

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant human protein was used as the immunogen for the GTF2I antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GTF2I antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the GTF2I antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu GTF2I

Target: GTF2I (General Transcription Factor III (GTF2I))

Andere Bezeichnung: GTF2I

Hintergrund: Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation. [UniProt]

UniProt: P78347