GTF2I Antikörper
Kurzübersicht für GTF2I Antikörper (ABIN7880865)
Target
Alle GTF2I Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- GTF2I Antibody / General transcription factor II-I (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant human protein was used as the immunogen for the GTF2I antibody.
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Isotyp
- IgG2b
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Applikationshinweise
- Optimal dilution of the GTF2I antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the GTF2I antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GTF2I (General Transcription Factor III (GTF2I))
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Andere Bezeichnung
- GTF2I
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Hintergrund
- Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation. [UniProt]
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UniProt
- P78347
Target
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