FGA Antikörper

Produktnummer ABIN7880785

Der Maus Monoklonal anti-FGA Antikörper (Klon UC45) (ABIN7880785) detektiert spezifisch FGA in ELISA, IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für FGA Antikörper (ABIN7880785)

Target: FGA (Fibrinogen alpha Chain (FGA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGA Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: UC45

Produktdetails anti-FGA Antikörper

Verwendungszweck: Fibrinogen Alpha Chain Antibody

Aufreinigung: PEG precipitation

Immunogen: Human acute monoblastic leukemia cells were used as the immunogen for the Fibrinogen Alpha Chain antibody.

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Fibrinogen Alpha Chain antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Fibrinogen Alpha Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu FGA

Target: FGA (Fibrinogen alpha Chain (FGA))

Andere Bezeichnung: Fibrinogen Alpha Chain

Hintergrund: The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.

UniProt: P02671