FGA Antikörper
Kurzübersicht für FGA Antikörper (ABIN7880784)
Target
Alle FGA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- Fibrinogen Alpha Chain Antibody (azide and preservative free)
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Aufreinigung
- PEG precipitation
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Immunogen
- Human acute monoblastic leukemia cells were used as the immunogen for the Fibrinogen Alpha Chain antibody.
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Isotyp
- IgM, kappa
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Applikationshinweise
- Optimal dilution of the Fibrinogen Alpha Chain antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the Fibrinogen Alpha Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- FGA (Fibrinogen alpha Chain (FGA))
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Andere Bezeichnung
- Fibrinogen Alpha Chain
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Hintergrund
- The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits. Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
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UniProt
- P02671
Target
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