Rekombinanter EMC4 Antikörper

Produktnummer ABIN7880733

Der Kaninchen Monoklonal anti-EMC4 Antikörper wird verwendet zum Nachweis von EMC4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC und IP.

Kurzübersicht für Rekombinanter EMC4 Antikörper (ABIN7880733)

Target: EMC4 (ER Membrane Protein Complex Subunit 4 (EMC4))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser EMC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Klon: 30E32

Produktdetails anti-EMC4 Antikörper

Verwendungszweck: EMC4 Antibody / ER membrane protein complex subunit 4

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human EMC4 was used as the immunogen for the EMC4 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the EMC4 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the EMC4 antibody at -20oC.

Details zu EMC4

Target: EMC4 (ER Membrane Protein Complex Subunit 4 (EMC4))

Andere Bezeichnung: EMC4

Hintergrund: EMC4 antibody recognizes ER membrane protein complex subunit 4, a component of the endoplasmic reticulum membrane complex (EMC). The EMC facilitates insertion of transmembrane proteins into the ER and aids in proper folding of multipass proteins. EMC4 plays a role in maintaining ER homeostasis and ensuring the quality control of membrane protein biosynthesis.

Research with EMC4 antibody has shown that loss of EMC function leads to defective protein targeting, ER stress, and activation of the unfolded protein response. EMC4 has also been linked to viral infection processes, where certain viruses hijack EMC components to ensure proper expression of their envelope proteins. These findings highlight EMC4's importance in both normal physiology and infectious disease biology.

Antibodies against EMC4 are validated in assays such as western blot, immunohistochemistry, and immunofluorescence. These reagents provide reliable detection of EMC4, allowing researchers to investigate ER protein insertion pathways and responses to cellular stress.

NSJ Bioreagents provides this EMC4 antibody for research on ER biology, membrane protein folding, and host-pathogen interactions. Alternate names include ER membrane protein complex subunit 4 antibody, EMC4A antibody, and transmembrane protein 93 antibody.

UniProt: Q5J8M3