ELP3/KAT9 Antikörper

Produktnummer ABIN7880676

Der Maus Monoklonal anti-ELP3/KAT9 Antikörper wird verwendet zum Nachweis von ELP3/KAT9 in Proben von Human, Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für ELP3/KAT9 Antikörper (ABIN7880676)

Target: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ELP3/KAT9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 8B4

Produktdetails anti-ELP3/KAT9 Antikörper

Verwendungszweck: Elongator complex protein 3 Antibody / ELP3 / KAT9

Sequenz: RDPTKFQHQG FGMLLMEEAE RIAREEH

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids RDPTKFQHQGFGMLLMEEAERIAREEH were used as the immunogen for the Elongator complex protein 3 antibody.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Elongator complex protein 3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Elongator complex protein 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ELP3/KAT9

Target: ELP3/KAT9 (ELP3) (Elongator complex protein 3 (ELP3))

Andere Bezeichnung: Elongator complex protein 3

Hintergrund: Elongator complex protein 3, also named KAT9, is a protein that in humans is encoded by the ELP3 gene. It is mapped to 8p21.1. ELP3 is the catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. ELP3 supports the migration and branching of projection neurons through acetylation of alpha-tubulin in the developing cerebral cortex. In mammals, ELP3 is important for paternal DNA demethylationafterfertilization.ELP3 is potentially involved in cellular redox homeostasis by mediating the acetylation ofglucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.

UniProt: Q9H9T3