Der Kaninchen Monoklonal anti-Doublecortin Antikörper (Klon AOAD-4) (ABIN7880653) detektiert spezifisch Doublecortin in WB.
Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.
Optimal dilution of the Doublecortin antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store the Doublecortin antibody at -20oC.
Target
Doublecortin (DCX)
Andere Bezeichnung
Doublecortin
Hintergrund
The neuronal migration protein Doublecortin is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. [UniProt]