CRY2 Antikörper

Produktnummer ABIN7880516

Dieser Maus Monoklonal Antikörper detektiert spezifisch CRY2 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für CRY2 Antikörper (ABIN7880516)

Target: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CRY2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 1819CT334-92-36-9

Produktdetails anti-CRY2 Antikörper

Verwendungszweck: CRY2 Antibody / Cryptochrome 2

Aufreinigung: Protein G purified

Immunogen: Recombinant human Cryptochrome 2 was used as the immunogen for the CRY2 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the CRY2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CRY2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CRY2

Target: CRY2 (Cryptochrome 2 (Photolyase-Like) (CRY2))

Andere Bezeichnung: CRY2

Hintergrund: Cryptochrome 2 is a transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time- keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. Transcription and translation of core clock components (CLOCK, NPAS2, ARNTL/BMAL1, ARNTL2/BMAL2, PER1, PER2, PER3, CRY1 and CRY2) plays a critical role in rhythm generation, whereas delays imposed by post-translational modifications (PTMs) are important for determining the period (tau) of the rhythms (tau refers to the period of a rhythm and is the length, in time, of one complete cycle). CRY1 and CRY2 have redundant functions but also differential and selective contributions at least in defining the pace of the SCN circadian clock and its circadian transcriptional outputs. CRY2 is a less potent transcriptional repressor in cerebellum and liver than CRY1, though less effective in lengthening the period of the SCN oscillator and seems to play a critical role in tuning SCN circadian period by opposing the action of CRY1. [UniProt]

UniProt: Q49AN0

Pathways: Response to Water Deprivation, Protein targeting to Nucleus