Rekombinanter CRTC2 Antikörper

Produktnummer ABIN7880510

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CRTC2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter CRTC2 Antikörper (ABIN7880510)

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CRTC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 28C77

Produktdetails anti-CRTC2 Antikörper

Verwendungszweck: CRTC2 Antibody / TORC2

Aufreinigung: Affinity chromatography

Immunogen: A synthetic peptide from human CREB-regulated transcription coactivator 2 protein was used as the immunogen for the CRTC2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CRTC2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the CRTC2 antibody at -20oC.

Details zu CRTC2

Target: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Andere Bezeichnung: CRTC2

Hintergrund: CRTC2 is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. [UniProt]

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis