Rekombinanter CDSE1 Antikörper

Produktnummer ABIN7880470

Der Kaninchen Monoklonal anti-CDSE1 Antikörper (Klon 30C82) (ABIN7880470) detektiert spezifisch CDSE1 in WB, IP, IHC, IF und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Rekombinanter CDSE1 Antikörper (ABIN7880470)

Target: CDSE1 (Cold Shock Domain Containing E1, RNA-Binding (CDSE1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CDSE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 30C82

Produktdetails anti-CDSE1 Antikörper

Verwendungszweck: CSDE1 Antibody / Cold shock domain containing E1

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human CSDE1 was used as the immunogen for the CSDE1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CSDE1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the CSDE1 antibody at -20oC.

Details zu CDSE1

Target: CDSE1 (Cold Shock Domain Containing E1, RNA-Binding (CDSE1))

Andere Bezeichnung: CSDE1

Hintergrund: CSDE1 antibody detects cold shock domain containing E1, an RNA binding protein encoded by the CSDE1 gene. CSDE1 contains five cold shock domains that mediate single stranded RNA binding, enabling regulation of mRNA stability, splicing, and translation. It associates with ribonucleoprotein complexes and influences the fate of transcripts involved in development, stress response, and tumorigenesis.

CSDE1 antibody is widely applied in RNA biology, cancer research, and developmental studies. CSDE1 promotes internal ribosome entry site (IRES) mediated translation of select mRNAs, enabling protein synthesis during conditions when cap dependent translation is impaired. It also regulates RNA turnover and processing through interactions with RNA binding proteins and decay machinery. By detecting CSDE1, researchers can evaluate how RNA binding proteins integrate post transcriptional control of gene expression.

Western blot assays detect CSDE1 protein bands in cytoplasmic fractions, while immunohistochemistry maps its distribution across epithelial and neuronal tissues. Immunofluorescence highlights punctate localization in ribonucleoprotein granules, consistent with functions in RNA storage and processing. These methods allow detailed characterization of CSDE1 expression and function.

CSDE1 plays important roles in tumorigenesis. In melanoma and other cancers, CSDE1 promotes oncogene expression and suppresses tumor suppressor translation. Elevated CSDE1 levels correlate with tumor progression, invasion, and metastasis. By applying CSDE1 antibody, scientists can investigate how post transcriptional regulation contributes to cancer biology and therapy resistance.

Beyond oncology, CSDE1 is implicated in embryonic development, neuronal differentiation, and stress adaptation. It influences neuronal polarity and axon growth, as well as cellular responses to hypoxia and nutrient deprivation. These broad functions highlight the research value of CSDE1 antibody across multiple biological fields.

CSDE1 antibody from NSJ Bioreagents provides dependable specificity for detecting this RNA binding regulator, supporting reliable analysis of RNA metabolism and translational control.

UniProt: O75534

Pathways: SARS-CoV-2 Protein Interaktom