Claudin 7 Antikörper

Produktnummer ABIN7880451

Der Kaninchen Polyklonal anti-Claudin 7 Antikörper wird verwendet zum Nachweis von Claudin 7 in Proben von Maus. Er wurde validiert für WB.

Kurzübersicht für Claudin 7 Antikörper (ABIN7880451)

Target: Claudin 7 (CLDN7)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Claudin 7 Antikörper

Verwendungszweck: Cldn7 Antibody / Claudin 7

Sequenz: SESKAAYRAP RSYPKSNSSK EYV

Aufreinigung: Affinity purified

Immunogen: Amino acids SESKAAYRAPRSYPKSNSSKEYV from the mouse protein were used as the immunogen for the Cldn7 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cldn7 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Cldn7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Claudin 7

Target: Claudin 7 (CLDN7)

Andere Bezeichnung: Cldn7

Hintergrund: Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed constitutively in the mammary epithelium throughout development, and might be involved in vesicle trafficking to the basolateral membrane. It is essential for NaCl homeostasis in distal nephrons. The knockout mice lacking this gene showed severe salt wasting, chronic dehydration, and growth retardation, and died within 12 days after birth. Alternatively spliced transcript variants have been found for this gene.

UniProt: Q9Z261

Pathways: Hepatitis C