Claudin 1 Antikörper

Produktnummer ABIN7880443

Der Kaninchen Monoklonal anti-Claudin 1 Antikörper (Klon ABEH-3) (ABIN7880443) detektiert spezifisch Claudin 1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Claudin 1 Antikörper (ABIN7880443)

Target: Claudin 1 (CLDN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Claudin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: ABEH-3

Produktdetails anti-Claudin 1 Antikörper

Verwendungszweck: CLDN1 Antibody / Claudin 1

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human Claudin 1 / CLDN1 was used as the immunogen for the CLDN1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CLDN1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the CLDN1 antibody at -20oC.

Details zu Claudin 1

Target: Claudin 1 (CLDN1)

Andere Bezeichnung: CLDN1

Hintergrund: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. [UniProt]

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C