CHI3L2 Antikörper

Produktnummer ABIN7880406

Der Maus Monoklonal anti-CHI3L2 Antikörper wird verwendet zum Nachweis von CHI3L2 in Proben von Human. Er wurde validiert für ELISA.

Kurzübersicht für CHI3L2 Antikörper (ABIN7880406)

Target: CHI3L2 (Chitinase 3-Like 2 (CHI3L2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHI3L2 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 1B2-G4

Produktdetails anti-CHI3L2 Antikörper

Verwendungszweck: CHI3L2 Antibody / Chitinase 3 like 2 / YKL-39

Aufreinigung: Protein G affinity

Immunogen: A recombinant YKL-39 partial protein was used as the immunogen for the CHI3L2 antibody.

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CHI3L2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CHI3L2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CHI3L2

Target: CHI3L2 (Chitinase 3-Like 2 (CHI3L2))

Andere Bezeichnung: CHI3L2

Hintergrund: The CHI3L2 protein, also known as chitinase-3-like protein 2, is a glycoprotein that belongs to the chitinase protein family. It is primarily associated with various biological processes, including inflammation, tissue remodeling, and immune responses. CHI3L2 is expressed in various tissues, such as the lungs, liver, and immune cells, suggesting its involvement in diverse physiological functions. CHI3L2 has been implicated in modulating immune responses and inflammatory processes. It is often associated with conditions characterized by inflammation, such as autoimmune diseases and certain cancers. The protein's precise mechanism of action is still under investigation, but it is believed to play a role in cell signaling and the regulation of cellular interactions within the immune system. HI3L2/YKL-39 has been explored as a biomarker in cancer diagnosis: Elevated levels of CHI3L2 in the serum or tissues have been investigated as potential biomarkers for cancer detection and prognosis. Monitoring CHI3L2 levels may aid in cancer diagnosis and assessment of disease progression. Inflammatory joint diseases, such as rheumatoid arthritis, have shown increased CHI3L2 expression. Detection of CHI3L2 levels in synovial fluid or blood may have diagnostic value in rheumatoid arthritis. CHI3L2/YKl-39 has also been explored as a biomarker for cardiovascular diseases. Elevated levels in the blood may indicate vascular inflammation and provide insights into cardiovascular risk.

UniProt: Q15782