CXCR2 Antikörper

Produktnummer ABIN7880400

Der Kaninchen Polyklonal anti-CXCR2 Antikörper wird verwendet zum Nachweis von CXCR2 in Proben von Human. Er wurde validiert für FACS und IHC (p).

Kurzübersicht für CXCR2 Antikörper (ABIN7880400)

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CXCR2 Antikörper

Verwendungszweck: CXCR2 Antibody

Sequenz: TLPPFLLDAA PCEPESLEIN K

Aufreinigung: Affinity purified

Immunogen: Amino acids TLPPFLLDAAPCEPESLEINK from the human protein were used as the immunogen for the CXCR2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CXCR2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CXCR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CXCR2

Target: CXCR2 (Chemokine (C-X-C Motif) Receptor 2 (CXCR2))

Andere Bezeichnung: CXCR2

Hintergrund: CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.

UniProt: P25025

Pathways: cAMP Metabolic Process