Rekombinanter CDC20 Antikörper
Kurzübersicht für Rekombinanter CDC20 Antikörper (ABIN7880379)
Target
Alle CDC20 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Recombinant Cdc20 Antibody
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Aufreinigung
- Protein A/G affinity
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Immunogen
- Recombinant human Cdc20 protein was used as the immunogen for the recombinant Cdc20 antibody.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal dilution of the recombinant Cdc20 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the recombinant Cdc20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))
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Andere Bezeichnung
- Cdc20
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Hintergrund
- Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. [UniProt]
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UniProt
- Q12834
Target
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