Rekombinanter DC-SIGN/CD209 Antikörper

Produktnummer ABIN7880259

Der Maus Monoklonal anti-DC-SIGN/CD209 Antikörper wird verwendet zum Nachweis von DC-SIGN/CD209 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter DC-SIGN/CD209 Antikörper (ABIN7880259)

Target: DC-SIGN/CD209 (CD209) (CD209)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RC209-1781

Produktdetails anti-DC-SIGN/CD209 Antikörper

Verwendungszweck: Recombinant CD209 Antibody / DC-SIGN

Aufreinigung: Protein G affinity chromatography

Immunogen: A human recombinant partial protein was used as the immunogen for this recombinant CD209 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant CD209 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant CD209 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: CD209

Hintergrund: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.

UniProt: Q9NNX6