DC-SIGN/CD209 Antikörper
Kurzübersicht für DC-SIGN/CD209 Antikörper (ABIN7880256)
Target
Alle DC-SIGN/CD209 (CD209) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Verwendungszweck
- CD209 Antibody / DC-SIGN (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant human DC-SIGN/CD209 protein fragment was used as the immunogen for the CD209 antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the CD209 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CD209 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DC-SIGN/CD209 (CD209) (CD209)
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Andere Bezeichnung
- CD209
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Hintergrund
- DC-SIGN/CD209 is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity.
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UniProt
- Q9NNX6
Target
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