CEBPZ Antikörper

Produktnummer ABIN7880220

Der Maus Monoklonal anti-CEBPZ Antikörper wird verwendet zum Nachweis von CEBPZ in Proben von Human. Er wurde validiert für FACS und IHC (p).

Kurzübersicht für CEBPZ Antikörper (ABIN7880220)

Target: CEBPZ (CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEBPZ Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: PCRP-CEBPZ-2D8

Produktdetails anti-CEBPZ Antikörper

Verwendungszweck: CEBPZ Antibody

Aufreinigung: Protein A/G affinity

Immunogen: The protein domain of CEBPZ protein was used as the immunogen for the CEBPZ antibody.

Isotyp: IgG2c

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CEBPZ antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CEBPZ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CEBPZ

Target: CEBPZ (CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ))

Andere Bezeichnung: CEBPZ

Hintergrund: C/EBPZ (CCAAT/enhancer-binding protein Z), also known as CBF, CBF2, NOC1 or HSP-CBF is a 1,054 amino acid nuclear protein belonging to the CBF/MAK21 family. C/EBPZ stimulates transcription from the HSP70 and HSP40 promoters in a NF-Y dependent manner, requiring an intact NF-Y trimer which binds to the DNA. C/EBPZ is thought to be a potential tumor suppressor gene, and aberrant methylation of the C/EBPZ promoter may be involved with acute myeloid leukemia. The C/EBPZ gene is conserved in a wide number of species including chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish and C. elegans and is located on human chromosome 2. Chromosome 2, the second largest human chromosome, consists of 237 million bases encoding over 1,400 genes, comprising approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2.

UniProt: Q03701