Der Kaninchen Monoklonal anti-BAG1 Antikörper wird verwendet zum Nachweis von BAG1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IF und IHC (p).
Optimal dilution of the BAG family molecular chaperone regulator 1 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store the BAG family molecular chaperone regulator 1 antibody at -20oC.
Target
BAG1
(BCL2-Associated Athanogene (BAG1))
Andere Bezeichnung
BAG family molecular chaperone regulator 1
Hintergrund
Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. [UniProt]