BCAM Antikörper

Produktnummer ABIN7880052

Der Kaninchen Polyklonal anti-BCAM Antikörper wird verwendet zum Nachweis von BCAM in Proben von Human, Maus und Ratte. Er wurde validiert für WB, FACS, IF und IHC (p).

Kurzübersicht für BCAM Antikörper (ABIN7880052)

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BCAM Antikörper

Verwendungszweck: BCAM Antibody / CD239

Sequenz: LLSLTSTLYL RLRKDDRDAS FHCAAHYSLP EGRH

Aufreinigung: Affinity purified

Immunogen: Amino acids LLSLTSTLYLRLRKDDRDASFHCAAHYSLPEGRH from the human protein were used as the immunogen for the BCAM antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the BCAM antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the BCAM antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu BCAM

Target: BCAM (Basal Cell Adhesion Molecule (Lutheran Blood Group) (BCAM))

Andere Bezeichnung: BCAM

Hintergrund: Basal cell adhesion molecule, also known as Lutheran antigen, is a plasma membraneglycoprotein that in humans is encoded by the BCAM gene. It is mapped to 19q13.32. This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P50895