ALOX5 Antikörper

Produktnummer ABIN7879995

Der Kaninchen Monoklonal anti-ALOX5 Antikörper wird verwendet zum Nachweis von ALOX5 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für ALOX5 Antikörper (ABIN7879995)

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ALOX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: AECE-1

Produktdetails anti-ALOX5 Antikörper

Verwendungszweck: 5-Lipoxygenase Antibody / ALOX5

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human 5-Lipoxygenase / ALOX5 was used as the immunogen for the 5-Lipoxygenase antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the 5-Lipoxygenase antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the 5-Lipoxygenase antibody at -20oC.

Details zu ALOX5

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Andere Bezeichnung: 5-Lipoxygenase

Hintergrund: The ALOX5 gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. [RefSeq]

UniProt: P09917