ALPL Antikörper

Produktnummer ABIN7879951

Der Kaninchen Polyklonal anti-ALPL Antikörper (ABIN7879951) detektiert spezifisch ALPL in WB, FACS, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ALPL Antikörper (ABIN7879951)

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALPL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ALPL Antikörper

Verwendungszweck: ALPL Antibody / Tissue-nonspecific Alkaline Phosphatase

Sequenz: KDPKYWRDQA QETLKYALEL Q

Aufreinigung: Affinity purified

Immunogen: Amino acids KDPKYWRDQAQETLKYALELQ from the human protein were used as the immunogen for the ALPL antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ALPL antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ALPL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu ALPL

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Andere Bezeichnung: ALPL

Hintergrund: Alkaline phosphatase (ALPL) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH . Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. ALPL is the alkaline phosphatase of skin fibroblasts, the tissue-nonspecific type, and that it is active toward millimolar concentrations of the putative natural substrates phosphoethanolamine (PEA) and pyridoxal-5-prime-phosphate (PLP). ALPL gene exists in single copy in the haploid genome and is composed of 12 exons distributed over more than 50 kb. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.

UniProt: P05186