ALDH1L1 Antikörper

Produktnummer ABIN7879932

Der Maus Monoklonal anti-ALDH1L1 Antikörper wird verwendet zum Nachweis von ALDH1L1 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für ALDH1L1 Antikörper (ABIN7879932)

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ALDH1L1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ALDH1L1-7968

Produktdetails anti-ALDH1L1 Antikörper

Verwendungszweck: 10-Formyltetrahydrofolate dehydrogenase Antibody / ALDH1L1

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment of human ALDH1L1 protein was used as the immunogen for the 10-Formyltetrahydrofolate dehydrogenase antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the 10-Formyltetrahydrofolate dehydrogenase antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the 10-Formyltetrahydrofolate dehydrogenase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu ALDH1L1

Target: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Andere Bezeichnung: 10-Formyltetrahydrofolate dehydrogenase

Hintergrund: Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH1L1 (aldehyde dehydrogenase 1 family member L1), also known as FTHFD or 10-FTHFD (10-formyltetrahydrofolate dehydrogenase), is a cytosolic protein that is developmentally regulated in the cerebellum. ALDH1L1 binds to folate and catalyzes the conversion of 10-formyltetrahydrofolate (10-FTHF) to tetrahydrofolate (THF). This suggests a possible role for ALDH1L1 in the regulation of cellular THF levels as well as in the inhibition of cell proliferation (as 10-FTHF is essential for the synthesis of purine). In addition, the overexpression of ALDH1L1 can restrict cell proliferation in vitro.

UniProt: O75891