APRT Antikörper

Produktnummer ABIN7879895

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch APRT in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für APRT Antikörper (ABIN7879895)

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APRT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-APRT Antikörper

Verwendungszweck: APRT Antibody

Sequenz: RAEVVECVSL VELTSLKGRE RL

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids RAEVVECVSLVELTSLKGRERL from the mouse protein were used as the immunogen for the APRT antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the APRT antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the APRT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu APRT

Target: APRT (Adenine Phosphoribosyltransferase (APRT))

Andere Bezeichnung: APRT

Hintergrund: Adenine phosphoribosyltransferase (APRTase) is an enzyme encoded by the APRT gene, found in humans on chromosome 16. It belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P08030

Pathways: Ribonucleoside Biosynthetic Process