Rekombinanter ACAT1 Antikörper

Produktnummer ABIN7879856

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch ACAT1 in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für Rekombinanter ACAT1 Antikörper (ABIN7879856)

Target: ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ACAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: 29A55

Produktdetails anti-ACAT1 Antikörper

Verwendungszweck: ACAT1 Antibody / Acetyl-CoA acetyltransferase

Aufreinigung: Affinity chromatography

Immunogen: A synthetic peptide specific to human Acetyl-CoA acetyltransferase protein was used as the immunogen for the ACAT1 Antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ACAT1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the ACAT1 antibody at -20oC.

Details zu ACAT1

Target: ACAT1 (Acetyl-CoA Acetyltransferase 1 (ACAT1))

Andere Bezeichnung: ACAT1

Hintergrund: The Acetyl-CoA acetyltransferase protein, also called ACAT1, is an enzyme that catalyzes the conversion of Acetyl-CoA to acetoacetyl-CoA. This reaction is a key step in the fatty acid beta-oxidation pathway, which is essential for the breakdown of fatty acids and the production of energy. Additionally, ACAT1 plays a critical role in ketogenesis, a process that occurs during times of fasting or low carbohydrate intake. The structure of the Acetyl-CoA acetyltransferase protein is highly conserved among different species, indicating its importance in cellular metabolism. This enzyme contains an active site where the catalytic reaction takes place, as well as binding sites for its substrate and cofactors. The precise mechanism by which Acetyl-CoA is converted to acetoacetyl-CoA by this enzyme involves a series of chemical reactions that involve the transfer of acetyl groups.

UniProt: P24752