Rekombinanter TIMP2 Antikörper (N-Term)
Kurzübersicht für Rekombinanter TIMP2 Antikörper (N-Term) (ABIN7879622)
Target
Alle TIMP2 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- N-Term
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Verwendungszweck
- Recombinant TIMP2 Antibody (azide and preservative free)
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Sequenz
- DSGNDIYGNP I
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Amino acids DSGNDIYGNPI (N-terminal region) were used as the immunogen for the recombinant TIMP2 antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the recombinant TIMP2 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the recombinant TIMP2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Andere Bezeichnung
- TIMP2
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Hintergrund
- It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
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UniProt
- P16035
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Pathways
- cAMP Metabolic Process
Target
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