MS4A6E Antikörper (N-Term)

Produktnummer ABIN7879621

Der Kaninchen Polyklonal anti-MS4A6E Antikörper (ABIN7879621) detektiert spezifisch MS4A6E in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MS4A6E Antikörper (N-Term) (ABIN7879621)

Target: MS4A6E (Membrane-Spanning 4-Domains, Subfamily A, Member 6E (MS4A6E))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MS4A6E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MS4A6E Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: MS4A6E Antibody / Membrane spanning 4-domains subfamily A member 6E

Aufreinigung: Immunogen affinity purified

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human MS4A6E was used as the immunogen for the MS4A6E antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MS4A6E antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MS4A6E antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MS4A6E

Target: MS4A6E (Membrane-Spanning 4-Domains, Subfamily A, Member 6E (MS4A6E))

Andere Bezeichnung: MS4A6E

Hintergrund: MS4A6E antibody detects Membrane spanning 4-domains subfamily A member 6E, encoded by the MS4A6E gene. MS4A6E is part of the MS4A protein family, which includes CD20, MS4A4A, and other membrane proteins involved in immune signaling and cellular communication. MS4A6E antibody provides researchers with a tool to study membrane biology, immune function, and disease processes associated with the MS4A family.

Membrane spanning 4-domains subfamily A member 6E is a predicted transmembrane protein with four membrane-spanning segments, but its precise cellular role remains under investigation. Research using MS4A6E antibody has suggested that it localizes to the plasma membrane and endosomal compartments. Like other MS4A family proteins, it may participate in signal transduction, calcium flux, or membrane organization.

Studies with MS4A6E antibody have demonstrated expression in immune-related tissues and the central nervous system. Genome-wide association studies have linked variants in MS4A6E to Alzheimer disease risk, suggesting functional involvement in neuroinflammation and amyloid processing. These findings highlight MS4A6E as a potential modulator of neurodegeneration through immune and signaling pathways.

In addition to neurological disease, MS4A6E expression changes have been observed in cancers. Research using MS4A6E antibody has shown that altered expression correlates with tumor progression and immune evasion. This suggests that MS4A6E may influence the tumor microenvironment and serve as a biomarker for certain malignancies.

MS4A6E antibody is commonly applied in western blotting, immunohistochemistry, and immunofluorescence. Western blotting detects protein expression in brain and immune tissues, immunohistochemistry localizes expression in tissue sections, and immunofluorescence reveals subcellular distribution. These approaches make MS4A6E antibody valuable for research into both immune and neurological biology.

By providing validated MS4A6E antibody reagents, NSJ Bioreagents supports studies into membrane proteins, neurodegeneration, and immune regulation. Detection of Membrane spanning 4-domains subfamily A member 6E provides researchers with insight into how MS4A proteins contribute to health and disease.

UniProt: Q96DS6