Rekombinanter MLANA Antikörper (N-Term)
Kurzübersicht für Rekombinanter MLANA Antikörper (N-Term) (ABIN7879618)
Target
Alle MLANA Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- N-Term
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Verwendungszweck
- MART-1 Antibody / Melan-A (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant fragment corresponding to the N-terminus of human Melan A protein was used as the immunogen for the MART-1 antibody.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal dilution of the MART-1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the MART-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MLANA (Melan A (MLANA))
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Andere Bezeichnung
- MART-1
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Hintergrund
- This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This mAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
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UniProt
- Q16655
Target
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