Der Maus Monoklonal anti-Tumor Protein p73 Antikörper wird verwendet zum Nachweis von Tumor Protein p73 in Proben von Human. Er wurde validiert für IHC (p).
TP73
Reaktivität: Human
WB, IHC, IF, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal dilution of the p73 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store the p73 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
Tumor Protein p73 (TP73)
(Tumor Protein P73 (TP73))
Andere Bezeichnung
p73
Hintergrund
The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.